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CD166 Antikörper (AA 167-406)

ALCAM Reaktivität: Human, Ratte, Maus WB, IHC, FACS, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5518801
  • Target Alle CD166 (ALCAM) Antikörper anzeigen
    CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))
    Bindungsspezifität
    • 16
    • 16
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 167-406
    Reaktivität
    • 105
    • 32
    • 25
    • 19
    • 4
    • 2
    • 1
    Human, Ratte, Maus
    Wirt
    • 80
    • 44
    • 3
    • 2
    • 2
    Kaninchen
    Klonalität
    • 79
    • 50
    • 1
    Polyklonal
    Konjugat
    • 67
    • 17
    • 13
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD166 Antikörper ist unkonjugiert
    Applikation
    • 85
    • 49
    • 48
    • 39
    • 29
    • 24
    • 13
    • 13
    • 12
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
    Verwendungszweck
    Anti-CD166/ALCAM Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins
    Produktmerkmale
    Anti-/ALCAM Antibody Picoband® (ABIN5518801). Tested in Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human CD166/ALCAM recombinant protein (Position: N167-E406). Human CD166/ALCAM shares 90.8% amino acid (aa) sequence identity with both mouse and rat CD166/ALCAM.
    Isotyp
    IgG
    Top Product
    Discover our top product ALCAM Primärantikörper
  • Applikationshinweise
    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
    Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
    1. Bowen MA, Patel DD, Li X, Modrell B, Malacko AR, Wang WC, Marquardt H, Neubauer M, Pesando JM, Francke U, et al. (Jun 1995). "Cloning, mapping, and characterization of activated leukocyte-cell adhesion molecule (ALCAM), a CD6 ligand". J Exp Med. 181 (6): 2213-20. 2. Fujiwara H, Tatsumi K, Kosaka K, et al. (2003). "Human blastocysts and endometrial epithelial cells express activated leukocyte cell adhesion molecule (ALCAM/CD166).".J. Clin. Endocrinol. Metab.88 (7): 3437-43.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target
    CD166 (ALCAM) (Activated Leukocyte Cell Adhesion Molecule (ALCAM))
    Andere Bezeichnung
    ALCAM (ALCAM Produkte)
    Hintergrund

    Synonyms: CD166 antigen,Activated leukocyte cell adhesion molecule,CD166,ALCAM,MEMD,

    Tissue Specificity: Spleen, placenta, liver, and weakly in liver. Expressed by activated T-cells, B-cells, monocytes and thymic epithelial cells. Expressed by neurons in the brain. Restricted expression in tumor cell lines. Preferentially expressed in highly metastasizing melanoma cell lines. .

    Background: This gene encodes activated leukocyte cell adhesion molecule (ALCAM), also known as CD166 (cluster of differentiation 166), which is a member of a subfamily of immunoglobulin receptors with five immunoglobulin-like domains (VVC2C2C2) in the extracellular domain. This protein binds to T-cell differentiation antigene CD6, and is implicated in the processes of cell adhesion and migration. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

    Molekulargewicht
    100-110 kDa
    Gen-ID
    214
    UniProt
    Q13740
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