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TUB Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TUB in WB und FACS. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN5518797

Kurzübersicht für TUB Antikörper (C-Term) (ABIN5518797)

Target

Alle TUB Antikörper anzeigen
TUB (Tubby Homolog (TUB))

Reaktivität

  • 12
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 13
  • 1
Kaninchen

Klonalität

  • 12
  • 2
Polyklonal

Konjugat

  • 14
Dieser TUB Antikörper ist unkonjugiert

Applikation

  • 14
  • 6
  • 5
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 4
    • 1
    • 1
    • 1
    • 1
    AA 395-429, C-Term

    Verwendungszweck

    Anti-TUB 1 Antibody Picoband®

    Sequenz

    VHERVSIRPR NEHETLLARW QNKNTESIIE LQNKT

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-TUB 1 Antibody Picoband® (ABIN5518797). Tested in Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    A synthetic peptide corresponding to a sequence at the C-terminus of human TUB 1, different from the related mouse and rat sequences by one amino acid.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    1. "Entrez Gene: TUB tubby homolog (mouse)". 2. Kapeller, R, Moriarty A, Strauss A, Stubdal H, Theriault K, Siebert E, Chickering T, Morgenstern J P, Tartaglia L A, Lillie J (Aug 1999). "Tyrosine phosphorylation of tub and its association with Src homology 2 domain-containing proteins implicate tub in intracellular signaling by insulin". J. Biol. Chem. UNITED STATES. 274 (35): 24980-6. 3. Kleyn PW, Fan W, Kovats SG, Lee JJ, Pulido JC, Wu Y, Berkemeier LR, Misumi DJ, Holmgren L, Charlat O, Woolf EA, Tayber O, Brody T, Shu P, Hawkins F, Kennedy B, Baldini L, Ebeling C, Alperin GD, Deeds J, Lakey ND, Culpepper J, Chen H, Glucksmann-Kuis MA, Carlson GA, Duyk GM, Moore KJ (Jun 1996). "Identification and characterization of the mouse obesity gene tubby: a member of a novel gene family". Cell. 85 (2): 281-90.

    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    TUB (Tubby Homolog (TUB))

    Andere Bezeichnung

    TUB

    Hintergrund

    Synonyms: Tubby protein homolog,TUB,

    Tissue Specificity: Ubiquitous.

    Background: Tubby protein homolog is a protein that in humans is encoded by the TUB gene. This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.

    Molekulargewicht

    62 kDa

    Gen-ID

    7275

    UniProt

    P50607

    Pathways

    RTK Signalweg, Sensory Perception of Sound
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