C5 Antikörper (C-Term)

Produktnummer ABIN5518715

Der Kaninchen Polyklonal anti-C5 Antikörper (ABIN5518715) detektiert spezifisch C5 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Ratte.

Kurzübersicht für C5 Antikörper (C-Term) (ABIN5518715)

Target: C5 (Complement Component 5 (C5))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-C5 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Anti-C5/C5a Antibody

Sequenz: TIADKIRKES HHKGMLLGR

Spezifität: No cross reactivity with other proteins.

Kreuzreaktivität (Details): No cross reactivity with other proteins

Homologie: different from the related mouse sequence by five amino acids.

Produktmerkmale: Anti-C5/C5a Antibody-1. Tested in WB applications. This antibody reacts with Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of rat C5a, different from the related mouse sequence by five amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL, Rat

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide, Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu C5

Target: C5 (Complement Component 5 (C5))

Andere Bezeichnung: C5

Hintergrund:

Background: C5a is a protein fragment released from complement component C5. This gene is mapped to 9q33.2. The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to susceptibility to liver fibrosis and to rheumatoid arthritis.

Gene Full Name: complement component 5

Sequence Similarities: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.

Molekulargewicht: 42 kDa

Gen-ID: 362119

UniProt: P08650

Pathways: Komplementsystem, Carbohydrate Homeostasis