COBRA1 Antikörper (N-Term)

Produktnummer ABIN5518104

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch COBRA1 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für COBRA1 Antikörper (N-Term) (ABIN5518104)

Target: COBRA1 (Cofactor of BRCA1 (COBRA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COBRA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-COBRA1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: NELFB Antibody - N-terminal region

Sequenz: NCTEPLKAIE QFQTENGVLL PSLQSALPFL DLHGTPRLEF HQSVFDELRD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 90%

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human COBRA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65310-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu COBRA1

Target: COBRA1 (Cofactor of BRCA1 (COBRA1))

Andere Bezeichnung: NELFB

Hintergrund:

Background Information: NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2, MIM 606026), either NELFC or NELFD (TH1L, MIM 605297), and NELFE (RDBP, MIM 154040). NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1, MIM 603555) and SPT5 (SUPT5H, MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]).[supplied by OMIM, Mar 2008]

Gene Name: negative elongation factor complex member B

Alternative Symbols: COBRA1, NELF-B

Protein Name: negative elongation factor B

Molekulargewicht: 66 kDa

Gen-ID: 25920

NCBI Accession: NP_056271

UniProt: Q8WX92