COBRA1 Antikörper

Produktnummer ABIN6657338

Produktdetails anti-COBRA1 Antikörper

Target: COBRA1 (Cofactor of BRCA1 (COBRA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser COBRA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human, Maus, Ratte (Rattus)

Aufreinigung: Anti-COBRA 1 antibody was Protein G purified from culture supernatant. This antibody is directed against human COBRA 1. Reactivity is expected against mouse and rat sources. Cross-reactivity from other sources has not been determined.

Immunogen:

Immunogen: Anti-COBRA1 Monoclonal Antibody was produced in mouse by repeated immunizations with recombinant full length human COBRA1 purified from E.coli.

Immunogen Type: Recombinant Protein

Klon: F7E4

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Application Note: Anti-COBRA 1 antibody is suitable for use in ELISA and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 62 kDa in size corresponding to COBRA1 proteins in neonatal rat brain lysate or other appropriate lysates.

ELISA Dilution: 1:10,000

Western Blot Dilution: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Details zu COBRA1

Target: COBRA1 (Cofactor of BRCA1 (COBRA1))

Andere Bezeichnung: COBRA 1 (COBRA1 Produkte)

Synonyme: LOC100219583 antikoerper, COBRA1 antikoerper, NELF-B antikoerper, bZ1O1.4 antikoerper, cobra1 antikoerper, cobra2 antikoerper, fe01e12 antikoerper, wu:fe01e12 antikoerper, zgc:55628 antikoerper, MGC131073 antikoerper, Cobra1 antikoerper, RGD1307832 antikoerper, A730008L03Rik antikoerper, AB041607 antikoerper, AI663983 antikoerper, Nelf-b antikoerper, cofactor of BRCA1 antikoerper, negative elongation factor complex member B antikoerper, negative elongation factor complex member B L homeolog antikoerper, LOC100219583 antikoerper, NELFB antikoerper, nelfb antikoerper, nelfb.L antikoerper, Nelfb antikoerper

Hintergrund:

Synonyms: COBRA1, Negative elongation factor B, NELF-B, Cofactor of BRCA1

Background: COBRA 1 antibody reacts with COBRA1 (cofactor of BRCA1) also known as NELF-B, which is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription. COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogeneis. Anti-COBRA 1 antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.

Gene Name: COBRA1

Gen-ID: 25920

UniProt: Q8WX92