Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

FAM57A Antikörper (C-Term)

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch FAM57A in WB. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN5518053

Kurzübersicht für FAM57A Antikörper (C-Term) (ABIN5518053)

Target

FAM57A (Family with Sequence Similarity 57, Member A (FAM57A))

Reaktivität

Human

Wirt

  • 1
Kaninchen

Klonalität

  • 1
Polyklonal

Konjugat

  • 1
Dieser FAM57A Antikörper ist unkonjugiert

Applikation

Western Blotting (WB)
  • Bindungsspezifität

    C-Term

    Sequenz

    QGLSLLQVPF SIPFYCNVAN AFLVAPQIYW FCLLCRKAVR LFDTPQAKKD

    Aufreinigung

    Affinity purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C terminal region of human FAM57A
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    FAM57A (Family with Sequence Similarity 57, Member A (FAM57A))

    Andere Bezeichnung

    FAM57A

    Hintergrund

    The protein encoded by this gene is a membrane-associated protein that promotes lung carcinogenesis. The encoded protein may be involved in amino acid transport and glutathione metabolism since it can interact with a solute carrier family member (SLC3A2) and an isoform of gamma-glutamyltranspeptidase-like 3. An alternatively spliced variant encoding a protein that lacks a 32 aa internal segment showed the opposite effect, inhibiting lung cancer cell growth. Knockdown of this gene also inhibited lung carcinogenesis and tumor cell growth. Several transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: CT120

    Protein Size: 225

    Gen-ID

    79850

    NCBI Accession

    NM_024792, NP_079068
Sie sind hier:
Chat with us!