FAM57A Antikörper (Middle Region)

Produktnummer ABIN5673967

Der Kaninchen Polyklonal anti-FAM57A Antikörper wird verwendet zum Nachweis von FAM57A in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für FAM57A Antikörper (Middle Region) (ABIN5673967)

Target: FAM57A (Family with Sequence Similarity 57, Member A (FAM57A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAM57A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FAM57A Antikörper

Bindungsspezifität: Middle Region

Sequenz: ELSTPFVSLG RVLIQLKQQH TLLYKVNGIL TLATFLSCRI LLFPFMYWSY

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FAM57A

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FAM57A

Target: FAM57A (Family with Sequence Similarity 57, Member A (FAM57A))

Andere Bezeichnung: FAM57A

Hintergrund: The protein encoded by this gene is a membrane-associated protein that promotes lung carcinogenesis. The encoded protein may be involved in amino acid transport and glutathione metabolism since it can interact with a solute carrier family member (SLC3A2) and an isoform of gamma-glutamyltranspeptidase-like 3. An alternatively spliced variant encoding a protein that lacks a 32 aa internal segment showed the opposite effect, inhibiting lung cancer cell growth. Knockdown of this gene also inhibited lung carcinogenesis and tumor cell growth. Several transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: CT120

Protein Size: 225

Gen-ID: 79850

NCBI Accession: NM_024792, NP_079068