COQ3 Antikörper (Middle Region)
Kurzübersicht für COQ3 Antikörper (Middle Region) (ABIN5517895)
Target
Alle COQ3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- CGGGLLTEPL GRLGASVIGI DPVDENIKTA QCHKSFDPVL DKRIEYRVCS
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 92%
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Produktmerkmale
- This is a rabbit polyclonal antibody against COQ3. It was validated on Western Blot.
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Aufreinigung
- Affinity purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human COQ3
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- COQ3 (Coenzyme Q3, Methyltransferase (COQ3))
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Andere Bezeichnung
- COQ3
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Hintergrund
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Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.
Alias Symbols: COQ3, UG0215E05,
Protein Size: 369 -
Gen-ID
- 51805
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NCBI Accession
- NP_059117
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UniProt
- Q9NZJ6
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Pathways
- Methionine Biosynthetic Process
Target
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