COQ3 Antikörper (AA 50-369)

Produktnummer ABIN6138894

Der Kaninchen Polyklonal anti-COQ3 Antikörper (ABIN6138894) detektiert spezifisch COQ3 in WB und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für COQ3 Antikörper (AA 50-369) (ABIN6138894)

Target: COQ3 (Coenzyme Q3, Methyltransferase (COQ3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COQ3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-COQ3 Antikörper

Bindungsspezifität: AA 50-369

Sequenz: PGVFNEYRTI WFKSYRTIFS CLNRIKSFRY PWARLYSTSQ TTVDSGEVKT FLALAHKWWD EQGVYAPLHS MNDLRVPFIR DNLLKTIPNH QPGKPLLGMK ILDVGCGGGL LTEPLGRLGA SVIGIDPVDE NIKTAQCHKS FDPVLDKRIE YRVCSLEEIV EETAETFDAV VASEVVEHVI DLETFLQCCC QVLKPGGSLF ITTINKTQLS YALGIVFSEQ IASIVPKGTH TWEKFVSPET LESILESNGL SVQTVVGMLY NPFSGYWHWS ENTSLNYAAY AVKSRVQEHP ASAEFVLKGE TEELQANACT NPAVHEKLKK

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 50-369 of human COQ3 (NP_059117.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu COQ3

Target: COQ3 (Coenzyme Q3, Methyltransferase (COQ3))

Andere Bezeichnung: COQ3

Hintergrund: Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.[supplied by OMIM, Mar 2008],COQ3,DHHBMT,DHHBMTASE,UG0215E05,bA9819.1,coenzyme Q3,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,COQ3

Molekulargewicht: 41 kDa

Gen-ID: 51805

UniProt: Q9NZJ6

Pathways: Methionine Biosynthetic Process