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COQ3 Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch COQ3 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Pferd und Schwein.
Produktnummer ABIN5517894

Kurzübersicht für COQ3 Antikörper (N-Term) (ABIN5517894)

Target

Alle COQ3 Antikörper anzeigen
COQ3 (Coenzyme Q3, Methyltransferase (COQ3))

Reaktivität

  • 25
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein

Wirt

  • 20
  • 5
Kaninchen

Klonalität

  • 23
  • 2
Polyklonal

Konjugat

  • 17
  • 2
  • 2
  • 2
  • 1
  • 1
Dieser COQ3 Antikörper ist unkonjugiert

Applikation

  • 20
  • 14
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 7
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    N-Term

    Sequenz

    ARLYSTSQTT VDSGEVKTFL ALAHKWWDEQ GVYAPLHSMN DLRVPFIRDN

    Homologie

    Cow: 79%, Dog: 86%, Horse: 86%, Human: 100%, Mouse: 92%, Pig: 79%, Rat: 93%

    Produktmerkmale

    This is a rabbit polyclonal antibody against COQ3. It was validated on Western Blot.

    Aufreinigung

    Affinity purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N-terminal region of Human COQ3
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    COQ3 (Coenzyme Q3, Methyltransferase (COQ3))

    Andere Bezeichnung

    COQ3

    Hintergrund

    Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.

    Alias Symbols: COQ3, UG0215E05,

    Protein Size: 369

    Gen-ID

    51805

    NCBI Accession

    NP_059117

    UniProt

    Q9NZJ6

    Pathways

    Methionine Biosynthetic Process
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