Tropomyosin Antikörper (N-Term)

Produktnummer ABIN5517707

Dieses Anti-Tropomyosin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Tropomyosin in WB. Geeignet für Human, Ratte, Maus, Zebrafisch (Danio rerio), Kaninchen, Rind (Kuh), Pferd und Schwein.

Kurzübersicht für Tropomyosin Antikörper (N-Term) (ABIN5517707)

Target: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Reaktivität: Human, Ratte, Maus, Zebrafisch (Danio rerio), Kaninchen, Rind (Kuh), Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tropomyosin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Tropomyosin Antikörper

Bindungsspezifität: N-Term

Sequenz: DAEADVASLN RRIQLVEEEL DRAQERLATA LQKLEEAEKA ADESERGMKV

Homologie: Cow: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TPM1. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TPM1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Tropomyosin

Target: Tropomyosin (TPM1) (Tropomyosin 1 (Alpha) (TPM1))

Andere Bezeichnung: TPM1

Hintergrund: This gene is a member of the tropomyosin family of highly conserved, widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle, where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells, alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy.

Alias Symbols: TPM1, C15orf13, TMSA,

Protein Interaction Partner: GOLGA2, CAGE1, C1orf216, SYCE1, KXD1, TFPT, MAD1L1, TPM4, TP53, TNNT1, UBC, MDM2, ETFA, FOXK1, KIAA1598, PPP6R3, APPL2, CDC37, MGEA5, STUB1, ABI2, DNAJC7, HSP90B1, PARK2, LRCH3, PAN2, TGFBR1, SPTBN1, ATF2, MDC1, BRCA1, PPP4R2, SRXN1, NUDCD2, RBM15, THOC2,

Protein Size: 284

Gen-ID: 7168

NCBI Accession: XP_006720731

UniProt: P09493

Pathways: Regulation of Actin Filament Polymerization