PKDCC Antikörper (N-Term)

Produktnummer ABIN5517602

Der Kaninchen Polyklonal anti-PKDCC Antikörper (ABIN5517602) detektiert spezifisch PKDCC in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PKDCC Antikörper (N-Term) (ABIN5517602)

Target: PKDCC (Protein Kinase Domain Containing, Cytoplasmic Homolog (Mouse) (PKDCC))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKDCC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PKDCC Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PKDCC Antibody - N-terminal region

Sequenz: GGRGELARQI RARYEEVQRY SRGGPGPGAG RPERRRLMDL APGGPGLPRP

Homologie: Cow: 100%, Dog: 78%, Human: 100%, Mouse: 100%

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PKDCC

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62899-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PKDCC

Target: PKDCC (Protein Kinase Domain Containing, Cytoplasmic Homolog (Mouse) (PKDCC))

Andere Bezeichnung: PKDCC

Hintergrund:

Background Information: Secreted tyrosine-protein kinase that mediates phosphorylation of extracellular proteins and endogenous proteins in the secretory pathway, which is essential for patterning at organogenesis stages. Mediates phosphorylation of MMP1, MMP13, MMP14, MMP19 and ERP29. Probably plays a role in platelets: rapidly and quantitatively secreted from platelets in response to stimulation of platelet degranulation. May also have serine/threonine protein kinase activity. Required for longitudinal bone growth through regulation of chondrocyte differentiation. May be indirectly involved in protein transport from the Golgi apparatus to the plasma membrane.

Gene Name: protein kinase domain containing, cytoplasmic

Alternative Symbols: Vlk, RLSDF, SGK493

Protein Name: Extracellular tyrosine-protein kinase PKDCC

Molekulargewicht: 54 kDa

Gen-ID: 91461

NCBI Accession: NP_612379

UniProt: Q504Y2