UBXN1 Antikörper (C-Term)

Produktnummer ABIN5517552

Produktdetails anti-UBXN1 Antikörper

Target: UBXN1 (UBX Domain Protein 1 (UBXN1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBXN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RAKKYGGSVG SQPPPVAPEP GPVPSSPSQE PPTKREYDQC RIQVRLPDGT

Produktmerkmale: This is a rabbit polyclonal antibody against UBXN1. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human UBXN1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu UBXN1

Target: UBXN1 (UBX Domain Protein 1 (UBXN1))

Andere Bezeichnung: UBXN1 (UBXN1 Produkte)

Synonyme: 2B28 antikoerper, SAKS1 antikoerper, UBXD10 antikoerper, 4930455J02Rik antikoerper, D19Ertd721e antikoerper, T25529 antikoerper, RGD1309471 antikoerper, fb49a05 antikoerper, wu:fb49a05 antikoerper, zgc:77531 antikoerper, UBX domain protein 1 antikoerper, UBXN1 antikoerper, Ubxn1 antikoerper, ubxn1 antikoerper

Hintergrund: UBXN1 is a ubiquitin-binding protein that interacts with the BRCA1- BARD1 heterodimer, and regulates its activity. It specifically binds 'Lys-6'-linked polyubiquitin chains. Interaction with autoubiquitinated BRCA1, it leads to inhibit the E3 ubiquitin-protein ligase activity of the BRCA1-BARD1 heterodimer. It is a component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulum that are retrotranslocated in the cytosol.

Alias Symbols: SAKS1

Protein Size: 297

Gen-ID: 51035

UniProt: Q04323