RORC Antikörper (N-Term)

Produktnummer ABIN5517298

Der Kaninchen Polyklonal Anti-RORC-Antikörper wurde für validiert. Er ist geeignet, RORC in Proben von Human, Ratte, Rind (Kuh), Pferd, Schwein und Saccharomyces cerevisiae zu detektieren.

Kurzübersicht für RORC Antikörper (N-Term) (ABIN5517298)

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Reaktivität: Human, Ratte, Rind (Kuh), Pferd, Schwein, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RORC Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Produktdetails anti-RORC Antikörper

Bindungsspezifität: N-Term

Sequenz: DSLHAEVQKQ LQQRQQQQQE PVVKTPPAGA QGADTLTYTL GLPDGQLPLG

Homologie: Cow: 92%, Horse: 85%, Human: 100%, Pig: 100%, Rat: 91%, Yeast: 100%

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RORG

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RORC

Target: RORC (RAR-Related Orphan Receptor C (RORC))

Andere Bezeichnung: RORC

Hintergrund: The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: TOR, RORG, RZRG, IMD42, NR1F3, RZR-GAMMA

Protein Interaction Partner: EVI2A, NCOA6, EIF3I, CHD4, EIF4EBP1,

Protein Size: 518

Gen-ID: 6097

NCBI Accession: NM_001001523, NP_001001523

UniProt: P51449

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway