PPP1R12B Antikörper (Middle Region)

Produktnummer ABIN5517282

Produktdetails anti-PPP1R12B Antikörper

Target: PPP1R12B (Protein Phosphatase 1, Regulatory Subunit 12B (PPP1R12B))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP1R12B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FNKPEEPKDE SPSSWRLGLR KTGSHNMLSE VANSREPIRD RGSSIYRSSS

Produktmerkmale: This is a rabbit polyclonal antibody against MYPT2. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen for Anti-PPP1R12B antibody is: synthetic peptide directed towards the Middle region of Human MYPT2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PPP1R12B

Target: PPP1R12B (Protein Phosphatase 1, Regulatory Subunit 12B (PPP1R12B))

Andere Bezeichnung: PPP1R12B (PPP1R12B Produkte)

Synonyme: 1810037O03Rik antikoerper, 9530009M10Rik antikoerper, AI132431 antikoerper, Mypt2 antikoerper, MYPT2 antikoerper, PP1bp55 antikoerper, protein phosphatase 1, regulatory subunit 12B antikoerper, protein phosphatase 1, regulatory (inhibitor) subunit 12B antikoerper, protein phosphatase 1 regulatory subunit 12B antikoerper, Ppp1r12b antikoerper, PPP1R12B antikoerper

Hintergrund: Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome.

Alias Symbols: MYPT2, PP1bp55

Protein Size: 982

Gen-ID: 4660

UniProt: O60237

Pathways: M Phase