PDE5A Antikörper (N-Term)

Produktnummer ABIN5517241

Der Kaninchen Polyklonal Anti-PDE5A-Antikörper wurde für WB validiert. Er ist geeignet, PDE5A in Proben von Human zu detektieren.

Kurzübersicht für PDE5A Antikörper (N-Term) (ABIN5517241)

Target: PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE5A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PDE5A Antikörper

Bindungsspezifität: N-Term

Sequenz: MERAGPSFGQ QRQQQQPQQQ KQQQRDQDSV EAWLDDHWDF TFSYFVRKAT

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PDE5A

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PDE5A

Target: PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

Andere Bezeichnung: PDE5A

Hintergrund: This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.

Alias Symbols: CN5A, PDE5, CGB-PDE

Protein Size: 875

Gen-ID: 8654

NCBI Accession: NM_001083, NP_001074

UniProt: O76074

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling