GZMH Antikörper (C-Term)

Produktnummer ABIN5516766

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GZMH in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für GZMH Antikörper (C-Term) (ABIN5516766)

Target: GZMH (Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GZMH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GZMH Antikörper

Bindungsspezifität: C-Term

Sequenz: EVLLTVQKDC QCERLFHGNY SRATEICVGD PKKTQTGFKG DSGGPLVCKD

Produktmerkmale: This is a rabbit polyclonal antibody against GZMH. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human GZMH

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GZMH

Target: GZMH (Granzyme H (Cathepsin G-Like 2, Protein H-CCPX) (GZMH))

Andere Bezeichnung: GZMH

Hintergrund: The protein encoded by this gene is a member of the granzyme family. Members of this family are highly conserved serine proteases that eliminate transformed cells and virus-infected cells. This protein, which has chymotrypsin-like activity, has a preference for bulky aromatic amino acids at the P1 position and for acidic residues at the P3' and P4' positions. This protein is reported to be constitutively expressed in NK cells and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Alias Symbols: GZMH, CGL2, CTSGL2,

Protein Interaction Partner: SSB,

Protein Size: 246

Gen-ID: 2999

NCBI Accession: NP_219491

UniProt: P20718