CD70 Antikörper (C-Term)

Produktnummer ABIN5516679

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CD70 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Rind (Kuh), Kaninchen, Pferd, Ratte, Schwein und Hund.

Kurzübersicht für CD70 Antikörper (C-Term) (ABIN5516679)

Target: CD70 (CD70 Molecule (CD70))

Reaktivität: Human, Maus, Rind (Kuh), Kaninchen, Pferd, Ratte, Schwein, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD70 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD70 Antikörper

Bindungsspezifität: C-Term

Sequenz: RLSFHQGCTI ASQRLTPLAR GDTLCTNLTG TLLPSRNTDE TFFGVQWVRP

Homologie: Cow: 86%, Dog: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 92%, Rabbit: 79%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against CD70. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CD70

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CD70

Target: CD70 (CD70 Molecule (CD70))

Andere Bezeichnung: CD70

Hintergrund: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.

Alias Symbols: CD27L, CD27LG, TNFSF7

Protein Interaction Partner: UBC, CD27, ELAVL1,

Protein Size: 193

Gen-ID: 970

NCBI Accession: NP_001243

UniProt: P32970

Pathways: Cancer Immune Checkpoints