NLRP12 Antikörper (N-Term)

Produktnummer ABIN5516341

Produktdetails anti-NLRP12 Antikörper

Target: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LEVSLVTPRK DPQETYRDYV RRKFRLMEDR NARLGECVNL SHRYTRLLLV

Homologie: Cow: 100%, Dog: 90%, Human: 100%, Mouse: 77%, Pig: 100%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against NLRP12. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human NLRP12

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NLRP12

Target: NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))

Andere Bezeichnung: NLRP12 (NLRP12 Produkte)

Synonyme: Nalp12 antikoerper, NALP12 antikoerper, CLR19.3 antikoerper, FCAS2 antikoerper, PAN6 antikoerper, PYPAF7 antikoerper, RNO antikoerper, RNO2 antikoerper, NLR family, pyrin domain containing 12 antikoerper, NLR family pyrin domain containing 12 antikoerper, NACHT, LRR and PYD domains-containing protein 3 antikoerper, Nlrp12 antikoerper, NLRP12 antikoerper, LOC100018508 antikoerper

Hintergrund: This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.

Alias Symbols: NLRP12, NALP12, PYPAF7, RNO,

Protein Interaction Partner: Dlg4, HSP90AA1, HSPA8, HSPA4, FAF1, IRAK1, PYCARD,

Protein Size: 1061

Gen-ID: 91662

NCBI Accession: NP_653288

UniProt: P59046

Pathways: Positive Regulation of Endopeptidase Activity, Inflammasome