GRP78 Antikörper (C-Term)

Produktnummer ABIN5516335

Der Kaninchen Polyklonal Anti-GRP78-Antikörper wurde für WB und IHC validiert. Er ist geeignet, GRP78 in Proben von Human, Ratte, Maus, Rind (Kuh), Kaninchen, Hund, Zebrafisch (Danio rerio), Meerschweinchen, Pferd und Ziege zu detektieren.

Kurzübersicht für GRP78 Antikörper (C-Term) (ABIN5516335)

Target: GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Kaninchen, Hund, Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRP78 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-GRP78 Antikörper

Bindungsspezifität: C-Term

Sequenz: LSSEDKETME KAVEEKIEWL ESHQDADIED FKAKKKELEE IVQPIISKLY

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against GRP78. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human GRP78

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GRP78

Target: GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

Andere Bezeichnung: GRP78

Hintergrund: The protein encoded by this gene is a member of the heat shock protein 70 (HSP70) family. It is localized in the lumen of the endoplasmic reticulum (ER), and is involved in the folding and assembly of proteins in the ER. As this protein interacts with many ER proteins, it may play a key role in monitoring protein transport through the cell.

Alias Symbols: HSPA5, GRP78,

Protein Interaction Partner: ERLIN2, HUWE1, GPX7, FUS, EP300, AMFR, UBC, RELA, LGALS3BP, AIRE, AURKB, CEP70, CEP76, HAUS2, TUBGCP4, CEP250, MAGED2, TUBGCP2, TUBGCP3, CEP57, TUBG1, TP53, AURKA, SUMO2, SUMO3, CLU, CDKN1A, CDC20, STAU1, SUMO1, NEDD8, MDM2, RPA3, RPA2, RPA1, EED, HSPA1L,

Protein Size: 654

Gen-ID: 3309

NCBI Accession: NP_005338

UniProt: P11021

Pathways: Thyroid Hormone Synthesis, ER-Nucleus Signaling