MERTK Antikörper (N-Term)
Kurzübersicht für MERTK Antikörper (N-Term) (ABIN5516110)
Target
Alle MERTK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- PEPVNIFWVQ NSSRVNEQPE KSPSVLTVPG LTEMAVFSCE AHNDKGLTVS
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Homologie
- Cow: 79%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against MERTK. It was validated on Western Blot.
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Aufreinigung
- Affinity purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human MERTK
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MERTK (C-Mer Proto-Oncogene Tyrosine Kinase (MERTK))
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Andere Bezeichnung
- MERTK
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Hintergrund
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This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).
Alias Symbols: MERTK, MER,
Protein Interaction Partner: UBC, HSP90AA1, TNK2, MERTK, ITGB5, NEDD4L, IKBKG, LMO4, BMPR2, GAS6, VAV1, GRB2,
Protein Size: 999 -
Gen-ID
- 10461
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NCBI Accession
- NP_006334
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UniProt
- Q12866
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Pathways
- RTK Signalweg
Target
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