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LITAF Antikörper (N-Term)
LITAF
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5516083
Produktdetails anti-LITAF Antikörper
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Target
Alle LITAF Antikörper anzeigen
LITAF
(Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))
Bindungsspezifität
Alle Epitope für LITAF Antikörper
N-Term
Reaktivität
Alle Reaktivitäten für LITAF Antikörper
Human
Wirt
Alle Wirte für LITAF Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für LITAF Antikörper
Polyklonal
Konjugat
Alle Konjugate für LITAF Antikörper
Dieser LITAF Antikörper ist unkonjugiert
Applikation
Alle Applikationen für LITAF Antikörper
Western Blotting (WB)
Sequenz
PSYEETVAVN SYYPTPPAPM PGPTTGLVTG PDGKGMNPPS YYTQPAPIPN
Produktmerkmale
This is a rabbit polyclonal antibody against LITAF. It was validated on Western Blot.
Aufreinigung
Affinity Purified
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human LITAF
Top Product
Discover our top product LITAF Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Details zu LITAF
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Target
LITAF
(Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))
Andere Bezeichnung
LITAF (LITAF Produkte )
Synonyme
PIG7 antikoerper, SIMPLE antikoerper, TP53I7 antikoerper, EET-1 antikoerper, Pig7 antikoerper, TNF-alpha antikoerper, 3222402J11Rik antikoerper, C85531 antikoerper, N4WBP3 antikoerper, TBX1 antikoerper, lipopolysaccharide induced TNF factor antikoerper, lipopolysaccharide-induced TNF factor antikoerper, LPS-induced TN factor antikoerper, LITAF antikoerper, Litaf antikoerper
Hintergrund
Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. Alias Symbols: LITAF, PIG7, SIMPLE, Protein Interaction Partner: REEP6, UBQLN1, STAM2, CALCOCO2, BAG3, HGS, UBC, STAT6, ATXN1, ITCH, TSG101, NEDD4, ELAVL1, RADIL, SMAD2, COMT, Protein Size: 228
Gen-ID
9516
Pathways
Cellular Response to Molecule of Bacterial Origin
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