INCENP Antikörper (C-Term)

Produktnummer ABIN5516066

Dieses Anti-INCENP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von INCENP in WB. Geeignet für Human, Ratte, Maus, Pferd, Schwein und Kaninchen.

Kurzübersicht für INCENP Antikörper (C-Term) (ABIN5516066)

Target: INCENP (Inner Centromere Protein Antigens 135/155kDa (INCENP))

Reaktivität: Human, Ratte, Maus, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INCENP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-INCENP Antikörper

Bindungsspezifität: C-Term

Sequenz: RELEEKKKKE EQQRLAERQL QEEQEKKAKE AAGASKALNV TVDVQSPACT

Homologie: Horse: 85%, Human: 100%, Mouse: 86%, Pig: 92%, Rabbit: 92%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against INCENP. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human INCENP

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu INCENP

Target: INCENP (Inner Centromere Protein Antigens 135/155kDa (INCENP))

Andere Bezeichnung: INCENP

Hintergrund: In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger,' or transiently interacting, proteins (reviewed by Choo, 1997). The constitutive proteins include CENPA, CENPB, CENPC1, and CENPD. The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle. These include CENPE, MCAK, KID, cytoplasmic dynein, CliPs, and CENPF/mitosin. The inner centromere proteins (INCENPs), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle progresses into mid-metaphase. During telophase, the proteins are located within the midbody in the intercellular bridge, where they are discarded after cytokinesis

Alias Symbols: INCENP,

Protein Interaction Partner: FLOT1, AURKB, HECW2, AURKC, AURKA, UBC, CDCA8, BIRC5, CBX5, HIST2H3C, SIRT7, Incenp, TUBA1A, EVI5, H2AFZ, SGOL1,

Protein Size: 918

Gen-ID: 3619

NCBI Accession: NP_064623

UniProt: Q9NQS7

Pathways: Zellzyklus