COPS8 Antikörper (N-Term)

Produktnummer ABIN5515908

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch COPS8 in WB. Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Hund und Zebrafisch (Danio rerio).

Kurzübersicht für COPS8 Antikörper (N-Term) (ABIN5515908)

Target: COPS8 (COP9 Signalosome Subunit 8 (COPS8))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COPS8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-COPS8 Antikörper

Bindungsspezifität: N-Term

Sequenz: QCENQELEAP GGIATPPVYG QLLALYLLHN DMNNARYLWK RIPPAIKSAN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against CSN8. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen for Anti-COPS8 antibody is: synthetic peptide directed towards the N-terminal region of Human CSN8

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu COPS8

Target: COPS8 (COP9 Signalosome Subunit 8 (COPS8))

Andere Bezeichnung: COPS8

Hintergrund: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Alias Symbols: COP9, CSN8, SGN8

Protein Interaction Partner: USHBP1, GPS1, cul1, WDR77, SRRT, COPS7A, VIM, COPS4, FBXO6, FBXW4, COPS5, vpr, IRF5, DDIT3, COPS2, COPS3, COPS6, PINK1, RFWD2, CUL4A, UBC, LRR1, DDA1, DDB2, DCUN1D1, VPRBP, CUL2, CUL3, CUL4B, CUL5, NEDD8, JUN, GFER, ERCC8, DDB1, CTNNB1, RAE1, COPS8, EIF3E

Protein Size: 209

Gen-ID: 10920

UniProt: Q99627

Pathways: Zellzyklus