CLK2 Antikörper (C-Term)

Produktnummer ABIN5515887

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CLK2 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für CLK2 Antikörper (C-Term) (ABIN5515887)

Target: CLK2 (CDC-Like Kinase 2 (CLK2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CLK2 Antikörper

Bindungsspezifität: C-Term

Sequenz: FDFLKDNNYL PYPIHQVRHM AFQLCQAVKF LHDNKLTHTD LKPENILFVN

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against CLK2. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human CLK2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CLK2

Target: CLK2 (CDC-Like Kinase 2 (CLK2))

Andere Bezeichnung: CLK2

Hintergrund: This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29 kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants.

Alias Symbols: CLK2,

Protein Interaction Partner: TRIM27, ECE1, CLK3, CLK2, YTHDC1, PRPF38A, LNX1, ZNF394, CPSF7, SNIP1, GMCL1, ZNF398, RSRP1, LUZP4, MRPL4, ZNF473, KLHL2, RNPS1, SRRM1, ZNF263, RBM39, ZRSR2, UBE2I, U2AF1, SRPK2, SDCBP, EED, ZNF30, FIP1L1, LUC7L, ZCCHC8, WDR33, CPSF2, PPHLN1, CPSF1, SETD2

Protein Size: 499

Gen-ID: 1196

NCBI Accession: XP_005276799

UniProt: P49760

Pathways: Regulation of Carbohydrate Metabolic Process