RAD52 Antikörper (Middle Region)

Produktnummer ABIN5515096

Der Kaninchen-Polyklonal Anti-RAD52-Antikörper wurde für WB validiert. Er ist geeignet zum Nachweis von RAD52 in Proben aus Human. }

Kurzübersicht für RAD52 Antikörper (Middle Region) (ABIN5515096)

Target: RAD52 (RAD52 Homolog (S. Cerevisiae) (RAD52))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD52 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RAD52 Antikörper

Bindungsspezifität: Middle Region

Sequenz: LNNGKFYVGV CAFVRVQLKD GSYHEDVGYG VSEGLKSKAL SLEKARKEAV

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RAD52

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RAD52

Target: RAD52 (RAD52 Homolog (S. Cerevisiae) (RAD52))

Andere Bezeichnung: RAD52

Hintergrund: The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52, a protein important for DNA double-strand break repair and homologous recombination. This gene product was shown to bind single-stranded DNA ends, and mediate the DNA-DNA interaction necessary for the annealing of complementary DNA strands. It was also found to interact with DNA recombination protein RAD51, which suggested its role in RAD51 related DNA recombination and repair. A pseudogene of this gene is present on chromosome 2. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Protein Size: 301

Gen-ID: 5893

NCBI Accession: NM_001297422, NP_001284348

UniProt: F5GX32

Pathways: DNA Reparatur