RAB43 Antikörper (C-Term)

Produktnummer ABIN5515092

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RAB43 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für RAB43 Antikörper (C-Term) (ABIN5515092)

Target: RAB43 (RAB43, Member RAS Oncogene Family (RAB43))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAB43 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RAB43 Antikörper

Bindungsspezifität: C-Term

Sequenz: ETSAKDSSNV EEAFLRVATE LIMRHGGPLF SEKSPDHIQL NSKDIGEGWG

Produktmerkmale: This is a rabbit polyclonal antibody against RAB43. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human RAB43

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RAB43

Target: RAB43 (RAB43, Member RAS Oncogene Family (RAB43))

Andere Bezeichnung: RAB43

Hintergrund: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. RAB43 is involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. It plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.

Alias Symbols: RAB41

Protein Size: 212

Gen-ID: 339122

NCBI Accession: NP_940892

UniProt: Q86YS6