Prolactin Receptor Antikörper (Middle Region)

Produktnummer ABIN5515079

Produktdetails anti-Prolactin Receptor Antikörper

Target: Prolactin Receptor (PRLR)

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Kaninchen, Hund, Ziege, Meerschweinchen, Pferd, Schaf, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Prolactin Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: WAVALKGYSM VTCIFPPVPG PKIKGFDAHL LEKGKSEELL SALGCQDFPP

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PRLR. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human PRLR

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Prolactin Receptor

Target: Prolactin Receptor (PRLR)

Andere Bezeichnung: PRLR (PRLR Produkte)

Synonyme: hPRLrI antikoerper, PRL-R antikoerper, prlr antikoerper, PRLRb antikoerper, PRLR antikoerper, tprlr antikoerper, DKFZp469D061 antikoerper, RATPRLR antikoerper, AI987712 antikoerper, Pr-1 antikoerper, Pr-3 antikoerper, Prlr-rs1 antikoerper, wu:fj65c07 antikoerper, prolactin receptor antikoerper, prolactin receptor L homeolog antikoerper, prolactin receptor S homeolog antikoerper, prolactin receptor a antikoerper, PRLR antikoerper, prlr.L antikoerper, prlr.S antikoerper, PR antikoerper, prlr antikoerper, Prlr antikoerper, prlra antikoerper

Hintergrund: This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.

Alias Symbols: PRLR,

Protein Interaction Partner: UBC, BTRC, STAT5B, PRLR, JAK2, CREBBP, FBXW11, CSH1, PRL, YWHAG, SOCS2, SOCS3, NEK3, CISH, YWHAZ, GHR, TEC, VAV2, ZAP70, PTPN11, VAV1, GH1, PPIA, GTF3A,

Protein Size: 622

Gen-ID: 5618

UniProt: P16471

Pathways: JAK-STAT Signalweg, Response to Growth Hormone Stimulus