Prolactin Receptor Antikörper (Middle Region)

Produktnummer ABIN5515079

Dieser Anti-Prolactin Receptor-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von Prolactin Receptor in WB. Geeignet für Human, Ratte, Maus, Rind (Kuh), Kaninchen, Hund, Ziege, Meerschweinchen, Pferd, Schaf und Zebrafisch (Danio rerio).

Kurzübersicht für Prolactin Receptor Antikörper (Middle Region) (ABIN5515079)

Target: Prolactin Receptor (PRLR)

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Kaninchen, Hund, Ziege, Meerschweinchen, Pferd, Schaf, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Prolactin Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Prolactin Receptor Antikörper

Bindungsspezifität: Middle Region

Sequenz: WAVALKGYSM VTCIFPPVPG PKIKGFDAHL LEKGKSEELL SALGCQDFPP

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PRLR. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human PRLR

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Prolactin Receptor

Target: Prolactin Receptor (PRLR)

Andere Bezeichnung: PRLR

Hintergrund: This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.

Alias Symbols: PRLR,

Protein Interaction Partner: UBC, BTRC, STAT5B, PRLR, JAK2, CREBBP, FBXW11, CSH1, PRL, YWHAG, SOCS2, SOCS3, NEK3, CISH, YWHAZ, GHR, TEC, VAV2, ZAP70, PTPN11, VAV1, GH1, PPIA, GTF3A,

Protein Size: 622

Gen-ID: 5618

UniProt: P16471

Pathways: JAK-STAT Signalweg, Response to Growth Hormone Stimulus