Prolactin Receptor Antikörper (C-Term)

Produktnummer ABIN5515078

Der Kaninchen Polyklonal anti-Prolactin Receptor Antikörper wird verwendet zum Nachweis von Prolactin Receptor in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für Prolactin Receptor Antikörper (C-Term) (ABIN5515078)

Target: Prolactin Receptor (PRLR)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Prolactin Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Prolactin Receptor Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: PRLR Antibody - C-terminal region

Sequenz: DGALSLLPKQ RENSGKPKKP GTPENNKEYA KVSGVMDNNI LVLVPDPHAK

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PRLR

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP80729-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Prolactin Receptor

Target: Prolactin Receptor (PRLR)

Andere Bezeichnung: PRLR

Hintergrund:

Background Information: This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.

Gene Name: prolactin receptor

Alternative Symbols: HPRL, MFAB, hPRLrI, RI-PRLR

Protein Name: prolactin receptor

Molekulargewicht: 68 kDa

Gen-ID: 5618

NCBI Accession: NP_000940

UniProt: P16471

Pathways: JAK-STAT Signalweg, Response to Growth Hormone Stimulus