IL-7 Antikörper (C-Term)

Produktnummer ABIN5514877

Der Kaninchen Polyklonal anti-IL-7 Antikörper wird verwendet zum Nachweis von IL-7 in Proben von Human, Schwein, Rind (Kuh), Hund, Pferd, Saccharomyces cerevisiae und Schaf. Er wurde validiert für WB.

Kurzübersicht für IL-7 Antikörper (C-Term) (ABIN5514877)

Target: IL-7 (IL7) (Interleukin 7 (IL7))

Reaktivität: Human, Schwein, Rind (Kuh), Hund, Pferd, Saccharomyces cerevisiae, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IL-7 Antikörper

Bindungsspezifität: C-Term

Sequenz: LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC

Homologie: Cow: 86%, Dog: 86%, Horse: 93%, Human: 100%, Pig: 100%, Sheep: 93%, Yeast: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against IL7. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human IL7

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IL-7

Target: IL-7 (IL7) (Interleukin 7 (IL7))

Andere Bezeichnung: IL7

Hintergrund: The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.

Alias Symbols: IL7,

Protein Interaction Partner: CEBPE, APP, IL2RG, IL7R,

Protein Size: 177

Gen-ID: 3574

UniProt: P13232

Pathways: JAK-STAT Signalweg