HIP1 Antikörper (C-Term)
Kurzübersicht für HIP1 Antikörper (C-Term) (ABIN5514846)
Target
Alle HIP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- IVESGRGTAS PKEFYAKNSR WTEGLISASK AVGWGATVMV DAADLVVQGR
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against HIP1. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human HIP1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HIP1 (Huntingtin Interacting Protein 1 (HIP1))
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Andere Bezeichnung
- HIP1
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Hintergrund
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The product of this gene is a membrane-associated protein that functions in clathrin-mediated endocytosis and protein trafficking within the cell. The encoded protein binds to the huntingtin protein in the brain, this interaction is lost in Huntington's disease. Alternative splicing results in multiple transcript variants.
Alias Symbols: HIP1,
Protein Interaction Partner: DAZAP2, REL, HIP1, FBXO25, CLTC, BFAR, ITSN1, UBC, MAPK6, HTT, HIP1R, IFT57, PFDN1, RPS10, EIF6, CASP9, APAF1, CASP8, AP2A1, AP2B1, CASP3, CLTB, CLTA, TFAP2A,
Protein Size: 1037 -
Gen-ID
- 3092
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NCBI Accession
- NP_005329
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UniProt
- O00291
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Pathways
- Positive Regulation of Endopeptidase Activity
Target
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