HIP1 Antikörper (C-Term)

Produktnummer ABIN5514846

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch HIP1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Meerschweinchen, Kaninchen, Rind (Kuh), Hund, Pferd und Zebrafisch (Danio rerio).

Kurzübersicht für HIP1 Antikörper (C-Term) (ABIN5514846)

Target: HIP1 (Huntingtin Interacting Protein 1 (HIP1))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Kaninchen, Rind (Kuh), Hund, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HIP1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: HIP1 Antibody - C-terminal region

Sequenz: IVESGRGTAS PKEFYAKNSR WTEGLISASK AVGWGATVMV DAADLVVQGR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against HIP1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human HIP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63595-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu HIP1

Target: HIP1 (Huntingtin Interacting Protein 1 (HIP1))

Andere Bezeichnung: HIP1

Hintergrund:

Background Information: The product of this gene is a membrane-associated protein that functions in clathrin-mediated endocytosis and protein trafficking within the cell. The encoded protein binds to the huntingtin protein in the brain, this interaction is lost in Huntington's disease. Alternative splicing results in multiple transcript variants.

Gene Name: huntingtin interacting protein 1

Alternative Symbols: SHON, HIP-I, ILWEQ, SHONbeta, SHONgamma

Protein Name: Huntingtin-interacting protein 1

Molekulargewicht: 114kDa

Gen-ID: 3092

NCBI Accession: NP_005329

UniProt: O00291

Pathways: Positive Regulation of Endopeptidase Activity