HIP1 Antikörper (C-Term)

Produktnummer ABIN2443742

Der Kaninchen Polyklonal anti-HIP1 Antikörper wird verwendet zum Nachweis von HIP1 in Proben von Human und Ratte. Er wurde validiert für WB und IF.

Kurzübersicht für HIP1 Antikörper (C-Term) (ABIN2443742)

Target: HIP1 (Huntingtin Interacting Protein 1 (HIP1))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-HIP1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Huntingtin-Interacting Protein 1 (HIP1) Rabbit Polyclonal Antibody

Spezifität: The antibody recognizes the C-terminal portion of HIP1

Aufreinigung: Purified

Immunogen: peptide in C term

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2500,IF 1:10-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: If diluted with deionized water in 100 μL: WB 1:500-1:2500, IF 1:10-1:100. Optimal dilution has to be determined by the user.

Buffer: Immunogen affinity purified in glycerol/PBS pH 7.4

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Antibodies diluted in glycerol can be kept at 4°C for up to 2 months and should be kept at -20°C for long-term storage (1 year). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. After the maximum long-term storage period (1 year -20°C or 2 months 4°C) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy.

Haltbarkeit: 12 months

Details zu HIP1

Target: HIP1 (Huntingtin Interacting Protein 1 (HIP1))

Andere Bezeichnung: Huntingtin-Interacting Protein 1 (HIP1)

Hintergrund:

HIP1

Hungtinton's disease (HD) is an inherited neurodegenerative disorder characterized by the expression of an expanded polyglutamine tract in the protein huntingtin. HIP1 (huntingtin interacting protein 1) binds to normal huntingtin but this interaction is lost in HD. HIP1 also binds to components of clathrin-coated pits and vesicles and is a marker of clathrin-coated membranes. HIP1 expression levels are altered in several types of cancer.

UniProt: O00291

Pathways: Positive Regulation of Endopeptidase Activity