Glutathione Synthetase Antikörper (C-Term)
Kurzübersicht für Glutathione Synthetase Antikörper (C-Term) (ABIN5514831)
Target
Alle Glutathione Synthetase (GSS) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- EEGDQAIAEA LAAPSRFVLK PQREGGGNNL YGEEMVQALK QLKDSEERAS
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Homologie
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against GSS. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human GSS
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Glutathione Synthetase (GSS)
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Andere Bezeichnung
- GSS
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Hintergrund
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Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency.
Alias Symbols: GSS,
Protein Interaction Partner: GSS, UBC, GINS3, OLA1, DCPS, ABHD14A, RRAGB, PDIA4, USP14, YWHAH, YWHAG, YWHAE, YWHAB, VCL, RAP1GDS1, PPP5C, PAFAH1B2, MVK, MSN, HMGB3, ECHS1, TBCB, ASS1, ASNS, CDK9, TERF1, GSTZ1,
Protein Size: 474 -
Gen-ID
- 2937
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NCBI Accession
- XP_005260463
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UniProt
- P48637
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Pathways
- Warburg Effekt
Target
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