FANCI Antikörper (C-Term)

Produktnummer ABIN5514761

Dieses Anti-FANCI-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von FANCI in WB. Geeignet für Human.

Kurzübersicht für FANCI Antikörper (C-Term) (ABIN5514761)

Target: FANCI (Fanconi Anemia Complementation Group I (FANCI))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FANCI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FANCI Antikörper

Bindungsspezifität: C-Term

Sequenz: MQHMKLSTSR DFKIKGNILD MVLREDGEDE NEEGTASEHG GQNKEPAKKK

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human FANCI

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FANCI

Target: FANCI (Fanconi Anemia Complementation Group I (FANCI))

Andere Bezeichnung: FANCI

Hintergrund: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group I. Alternative splicing results in two transcript variants encoding different isoforms.

Alias Symbols: KIAA1794

Protein Size: 1268

Gen-ID: 55215

NCBI Accession: NM_001113378, NP_001106849

Pathways: DNA Reparatur