E2F2 Antikörper (Middle Region)

Produktnummer ABIN5514732

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch E2F2 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio) und Schwein.

Kurzübersicht für E2F2 Antikörper (Middle Region) (ABIN5514732)

Target: E2F2 (E2F Transcription Factor 2 (E2F2))

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser E2F2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-E2F2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: CSLSFKHLTE DKANKRLAYV TYQDIRAVGN FKEQTVIAVK APPQTRLEVP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 87%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 100%, Zebrafish: 75%

Produktmerkmale: This is a rabbit polyclonal antibody against E2F2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human E2F2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu E2F2

Target: E2F2 (E2F Transcription Factor 2 (E2F2))

Andere Bezeichnung: E2F2

Hintergrund: E2F2 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain.

Alias Symbols: E2F-2

Protein Interaction Partner: RB1, GNB5, GIT2, TFDP1, RBL1, ARID3A, ELAVL1, ATAD2, KMT2D, KMT2A, RYBP, SETD8, BCAR1, TFDP2, BRD2, YY1, SP1, CDK3, RNF144A, FHL2, SPIB, RBL2, E2F4, MYBL2, EAPP, TP53BP2, PPP1R13B, TP53INP1, JMY, GAB2, CDC25A, CDC6, E2F1, UXT, MT1G,

Protein Size: 437

Gen-ID: 1870

NCBI Accession: NM_004091, NP_004082

UniProt: Q14209

Pathways: Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication