CEP290 Antikörper (N-Term)

Produktnummer ABIN5514637

Der Kaninchen Polyklonal anti-CEP290 Antikörper wird verwendet zum Nachweis von CEP290 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für CEP290 Antikörper (N-Term) (ABIN5514637)

Target: CEP290 (Centrosomal Protein 290kDa (CEP290))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CEP290 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CEP290 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: CEP290 Antibody - N-terminal region

Sequenz: EQLCQDIIDY QKQIDSQKET LLSRRGEDSD YRSQLSKKNY ELIQYLDEIQ

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CEP290

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP80284-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CEP290

Target: CEP290 (Centrosomal Protein 290kDa (CEP290))

Andere Bezeichnung: CEP290

Hintergrund:

Background Information: This gene encodes a protein with 13 putative coiled-coil domains, a region with homology to SMC chromosome segregation ATPases, six KID motifs, three tropomyosin homology domains and an ATP/GTP binding site motif A. The protein is localized to the centrosome and cilia and has sites for N-glycosylation, tyrosine sulfation, phosphorylation, N-myristoylation, and amidation. Mutations in this gene have been associated with Joubert syndrome and nephronophthisis and the presence of antibodies against this protein is associated with several forms of cancer.

Gene Name: centrosomal protein 290 kDa

Alternative Symbols: CT87, MKS4, POC3, rd16, BBS14, JBTS5, LCA10, NPHP6, SLSN6, 3H11Ag

Protein Name: centrosomal protein of 290 kDa

Molekulargewicht: 88 kDa

Gen-ID: 80184

NCBI Accession: NP_079390

UniProt: Q05BJ6

Pathways: cAMP Metabolic Process, M Phase