beta Synuclein Antikörper (C-Term)
Kurzübersicht für beta Synuclein Antikörper (C-Term) (ABIN5514426)
Target
Alle beta Synuclein (SNCB) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Verwendungszweck
- SNCB Antibody - C-terminal region
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Sequenz
- GLVKREEFPT DLKPEEVAQE AAEEPLIEPL MEPEGESYED PPQEEYQEYE
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Homologie
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 86%, Rat: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against SYUB. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human SNCB
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33883-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- beta Synuclein (SNCB) (Synuclein, beta (SNCB))
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Andere Bezeichnung
- SNCB
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Hintergrund
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Background Information: The protein encoded by this gene is highly homologous to alpha-synuclein. These proteins are abundantly expressed in the brain and putatively inhibit phospholipase D2 selectively. The encoded protein, which may play a role in neuronal plasticity, is abundant in neurofibrillary lesions of patients with Alzheimer disease. This protein has been shown to be highly expressed in the substantia nigra of the brain, a region of neuronal degeneration in patients with Parkinson disease, however, no direct relation to Parkinson disease has been established. Two transcript variants encoding the same protein have been found for this gene.
Gene Name: synuclein, beta
Alternative Symbols: SNCB, Beta-synuclein
Protein Name: Beta-synuclein
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Molekulargewicht
- 14kDa
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Gen-ID
- 6620
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NCBI Accession
- XP_006714979
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UniProt
- Q16143
Target
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