TFAM
Reaktivität: Human
WB, IHC, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
In 1x PBS, pH 7.4
Handhabung
Aliquot to avoid repeated freezing and thawing.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Takeda, Hasegawa, Ueha, Sakakibara, Kawamoto, Minamikawa, Sakai, Komori: "Decreased mitochondrial copy numbers in oral squamous cell carcinoma." in: Head & neck, Vol. 38, Issue 8, pp. 1170-5, (2016) (PubMed).
Morishita, Kawamoto, Hara, Onishi, Ueha, Minoda, Katayama, Takemori, Fukase, Kurosaka, Kuroda, Akisue: "AICAR induces mitochondrial apoptosis in human osteosarcoma cells through an AMPK-dependent pathway." in: International journal of oncology, Vol. 50, Issue 1, pp. 23-30, (2016) (PubMed).
Akbari, Sykora, Bohr: "Slow mitochondrial repair of 5'-AMP renders mtDNA susceptible to damage in APTX deficient cells." in: Scientific reports, Vol. 5, pp. 12876, (2015) (PubMed).
Akbari, Keijzers, Maynard, Scheibye-Knudsen, Desler, Hickson, Bohr: "Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair." in: DNA repair, Vol. 16, pp. 44-53, (2014) (PubMed).
Gibellini, Pinti, Boraldi, Giorgio, Bernardi, Bartolomeo, Nasi, De Biasi, Missiroli, Carnevale, Losi, Tesei, Pinton, Quaglino, Cossarizza: "Silencing of mitochondrial Lon protease deeply impairs mitochondrial proteome and function in colon cancer cells." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 12, pp. 5122-35, (2014) (PubMed).
Gispert, Parganlija, Klinkenberg, Dröse, Wittig, Mittelbronn, Grzmil, Koob, Hamann, Walter, Büchel, Adler, Hrabé de Angelis, Busch, Zell, Reichert, Brandt, Osiewacz, Jendrach, Auburger: "Loss of mitochondrial peptidase Clpp leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors." in: Human molecular genetics, Vol. 22, Issue 24, pp. 4871-87, (2013) (PubMed).
Rolland, Motori, Memar, Hench, Frank, Winklhofer, Conradt: "Impaired complex IV activity in response to loss of LRPPRC function can be compensated by mitochondrial hyperfusion." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 32, pp. E2967-76, (2013) (PubMed).
Holmström, Iglesias-Gutierrez, Zierath, Garcia-Roves: "Tissue-specific control of mitochondrial respiration in obesity-related insulin resistance and diabetes." in: American journal of physiology. Endocrinology and metabolism, Vol. 302, Issue 6, pp. E731-9, (2012) (PubMed).
Aamann, Sorensen, Hvitby, Berquist, Muftuoglu, Tian, de Souza-Pinto, Scheibye-Knudsen, Wilson, Stevnsner, Bohr: "Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 7, pp. 2334-46, (2010) (PubMed).
Target
TFAM
(Transcription Factor A, Mitochondrial (TFAM))