Angiopoietin 1 Antikörper (C-Term)

Produktnummer ABIN504734

Der Kaninchen Polyklonal Anti-Angiopoietin 1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, Angiopoietin 1 in Proben von Human, Maus und Kaninchen zu detektieren.

Kurzübersicht für Angiopoietin 1 Antikörper (C-Term) (ABIN504734)

Target: Angiopoietin 1 (ANGPT1)

Reaktivität: Human, Maus, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Angiopoietin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Angiopoietin 1 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Hund, Human, Kaninchen, Ratte (Rattus)

Aufreinigung: affinity purified

Immunogen: C-terminal sequence of human Angiopoietin-1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: -20 °C

Details zu Angiopoietin 1

Target: Angiopoietin 1 (ANGPT1)

Andere Bezeichnung: Angiopoietin-1

Hintergrund: Angiopoietin 1 is one of the Angiopoietin (Ang) family of growth factors. It binds and activates the TIE2 receptor tyrosine kinase by inducing its tyrosine phosphorylation. It is implicated in endothelial developmental processes later and distinct from that of VEGF. The structure of angiopoietin 1 differs from that of known angiogenic factors or other ligands for receptor tyrosine kinases. Angiopoietin 1 appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. It also mediates blood vessel maturation/stability and it may play an important role in the heart early development. Angiopoietin 1 may have a potential therapeutic utility since it can be used for specifically targeting tumor vasculature or for promoting angiogenic processes in certain organs such as an ischemic heart.

Pathways: RTK Signalweg, Glycosaminoglycan Metabolic Process