14-3-3 theta Antikörper

Produktnummer ABIN5027747

Dieses Anti-14-3-3 theta-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von 14-3-3 theta in WB. Geeignet für Maus.

Kurzübersicht für 14-3-3 theta Antikörper (ABIN5027747)

Target: 14-3-3 theta (YWHAQ)

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser 14-3-3 theta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: ABM52H6

Produktdetails anti-14-3-3 theta Antikörper

Aufreinigung: Protein G Chromatography

Immunogen: Full length recombinant protein of 14-3-3 Theta was used as the immunogen for this antibody.

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: WB: 2-4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu 14-3-3 theta

Target: 14-3-3 theta (YWHAQ)

Andere Bezeichnung: 14-3-3 Theta

Hintergrund: 14-3-3 Theta, a member of 14-3-3 family, is an adapter protein that plays an important role in a wide range of vital regulatory processes, including signal transduction, apoptosis, cell cycle progression and DNA replication. Humans have seven 14-3-3 isoforms (beta, gamma, epsilon, eta, sigma, theta and zeta) that serve as scaffolds to promote interactions of regulatory phospho-proteins involved in many vital cellular processes. 14-3-3 Theta binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif, resulting in the modulation of the activity of the binding partner except PDPK1, whose kinase activity is negatively regulated. Previous studies have shown that disturbances in native 14-3-3 levels can contribute significantly to the development of various cancers. In lung cancer biopsies, 14-3-3 Theta is found to be present in abundance.

Molekulargewicht: 27 kDa

Gen-ID: 10971

UniProt: P27348

Pathways: Apoptose, Myometrial Relaxation and Contraction