Villin 1 Antikörper (AA 108-322)

Produktnummer ABIN5027631

Dieser Maus Monoklonal Antikörper detektiert spezifisch Villin 1 in IHC und WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Villin 1 Antikörper (AA 108-322) (ABIN5027631)

Target: Villin 1 (VIL1)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Villin 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Klon: ABM4E64

Produktdetails anti-Villin 1 Antikörper

Bindungsspezifität: AA 108-322

Aufreinigung: Protein G Chromatography

Immunogen: A partial length recombinant Villin protein (amino acids 108-322) was used as the immunogen for this antibody.

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: WB: 0.5 μg/mL, IHC-5-10 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu Villin 1

Target: Villin 1 (VIL1)

Andere Bezeichnung: Villin

Hintergrund: Villin is a protein that belongs to the gelsolin family of calcium-regulated actin-binding proteins. It is expressed in differentiated epithelial cells with a brush border such as intestinal villi, proximal renal tubules, oviduct, and seminiferous ducts. Villin shares structural and functional homology with two conserved families of proteins. One family of proteins, which includes gelsolin and adseverin, shares the conserved domain(s) found in the villin core. Villin regulates cell migration, cell death, and epithelial-to-mesenchymal transition underscoring the significance of this protein to epithelial cell function.

Molekulargewicht: 90 kDa

Gen-ID: 396423

UniProt: P09327

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization