TRBP Antikörper (AA 150-366)

Produktnummer ABIN5027591

Produktdetails anti-TRBP Antikörper

Target: TRBP (TARBP2P) (TAR (HIV-1) RNA Binding Protein 2 Pseudogene (TARBP2P))

Bindungsspezifität: AA 150-366

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant TRBP protein (amino acids 150-366) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 6-7 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu TRBP

Target: TRBP (TARBP2P) (TAR (HIV-1) RNA Binding Protein 2 Pseudogene (TARBP2P))

Andere Bezeichnung: TRBP (TARBP2P Produkte)

Synonyme: TRBP antikoerper, TARBP2P1, RISC loading complex RNA binding subunit pseudogene 1 antikoerper, TARBP2P1 antikoerper

Hintergrund: TRBP, also known as TARBP2 (TAR (HIV-1) RNA binding protein 2) is a contributory agent of acquired immunodeficiency syndrome (AIDS). TRBP binds between the bulge and the loop of the HIV-1 TAR RNA regulatory element and activates HIV-1 gene expression in synergy with the viral Tat protein. It also plays a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1 and promotes translation of TAR-containing RNAs independently of EIF2AK2/PKR. Diseases associated with TARBP2 include acquired immunodeficiency syndrome. TARBP2 is highly expressed in adipose tissue, adrenal cortex, adrenal gland, amniotic fluid and amygdala. TRBP exists in two isoforms whereas alternate splicing results in multiple transcript variants encoding different isoforms. This gene also has a pseudogene.

Molekulargewicht: 48 KDa

Gen-ID: 6895

UniProt: Q15633

Pathways: Regulatorische RNA Pathways, Ribonucleoprotein Complex Subunit Organization