TOX3 Antikörper (AA 232-442)

Produktnummer ABIN5027585

Dieses Anti-TOX3-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von TOX3 in WB und IHC. Geeignet für Human.

Kurzübersicht für TOX3 Antikörper (AA 232-442) (ABIN5027585)

Target: TOX3 (TOX High Mobility Group Box Family Member 3 (TOX3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TOX3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: ABM44A1

Produktdetails anti-TOX3 Antikörper

Bindungsspezifität: AA 232-442

Aufreinigung: Protein G Chromatography

Immunogen: A partial length recombinant TOX-3 protein (amino acids 232-442) was used as the immunogen for this antibody

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: WB: 2-4 μg/mL, IHC: 5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu TOX3

Target: TOX3 (TOX High Mobility Group Box Family Member 3 (TOX3))

Andere Bezeichnung: TOX-3

Hintergrund: TOX high mobility group box family member 3 (TOX-3) is a member of a subfamily of transcription factors that contains a High Mobility Group box (HMG-box), involved in bending and unwinding of DNA and alteration of chromatin structure. It has two transcript variants encoding different isoforms.TOX3 is expressed in estrogen receptor-positive mammary epithelial cells, including progenitor cells and highly expressed in luminal B breast cancers. Its over expression in human oligodendrocytes reduced cellular death under conditions mimicking Spinal cord injury (SCI).

Molekulargewicht: 63 kDa

Gen-ID: 27324

UniProt: O15405

Pathways: Chromatin Binding