RAGE Antikörper (AA 1-280)

Produktnummer ABIN5027503

Der Kaninchen Polyklonal anti-RAGE Antikörper wird verwendet zum Nachweis von RAGE in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für RAGE Antikörper (AA 1-280) (ABIN5027503)

Target: RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAGE Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RAGE Antikörper

Bindungsspezifität: AA 1-280

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant RAGE protein (amino acids 1-280) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu RAGE

Target: RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

Andere Bezeichnung: RAGE

Hintergrund: RAGE (Advanced glycosylation end product-specific receptor) is a member of immunoglobulin superfamily with multiple isoforms being located on the membrane of endothelial cells. RAGE acts transporter of amyloid beta peptide across the blood brain barrier. It has also been reported that RAGE is overexpressed in Alzheimer disease. RAGE is also involved in vascular inflammation in atherosclerosis, type 2 diabetes mellitus. High levels of RAGE protein is found in brain tissue.

Molekulargewicht: 42 kDa

Gen-ID: 177

UniProt: Q15109

Pathways: Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteine