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NLRP3 Antikörper (AA 150-385)
NLRP3
Reaktivität: Human, Maus
WB, IHC
Wirt: Maus
Monoclonal
ABM2D48
unconjugated
Produktnummer ABIN5027384
Produktdetails anti-NLRP3 Antikörper
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Target
Alle NLRP3 Antikörper anzeigen
NLRP3
(NLR Family, Pyrin Domain Containing 3 (NLRP3))
Bindungsspezifität
Alle Epitope für NLRP3 Antikörper
AA 150-385
Reaktivität
Alle Reaktivitäten für NLRP3 Antikörper
Human, Maus
Wirt
Alle Wirte für NLRP3 Antikörper
Maus
Klonalität
Alle Klonalitäten für NLRP3 Antikörper
Monoklonal
Konjugat
Alle Konjugate für NLRP3 Antikörper
Dieser NLRP3 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für NLRP3 Antikörper
Western Blotting (WB), Immunohistochemistry (IHC)
Aufreinigung
Protein G Chromatography
Immunogen
A partial length recombinant NALP3 protein (amino acids 150-385) was used as the immunogen for this antibody.
Klon
ABM2D48
Isotyp
IgG2b kappa
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Discover our top product NLRP3 Primärantikörper
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anti-NLR Family, Pyrin Domain Containing 3 (NLRP3) (AA 15-120) antibody
NLRP3
Reaktivität: Human, Maus, Ratte, Hund
WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
WB: 6-8 μg/mL, IHC: 5 μg/mL
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Details zu NLRP3
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Target
NLRP3
(NLR Family, Pyrin Domain Containing 3 (NLRP3))
Andere Bezeichnung
NALP3 (NLRP3 Produkte )
Synonyme
CIAS1 antikoerper, Nalp3 antikoerper, avp antikoerper, cias1 antikoerper, nalp3 antikoerper, pypaf1 antikoerper, agtavprl antikoerper, AGTAVPRL antikoerper, AII antikoerper, AVP antikoerper, C1orf7 antikoerper, CLR1.1 antikoerper, FCAS antikoerper, FCU antikoerper, MWS antikoerper, NALP3 antikoerper, PYPAF1 antikoerper, AII/AVP antikoerper, Cias1 antikoerper, Mmig1 antikoerper, Pypaf1 antikoerper, NLR family pyrin domain containing-like antikoerper, NLR family pyrin domain containing 3 antikoerper, NLR family, pyrin domain containing 3 L homeolog antikoerper, NLR family, pyrin domain containing 3 antikoerper, NLRPL antikoerper, NLRP3 antikoerper, nlrp3.L antikoerper, Nlrp3 antikoerper
Hintergrund
NALP3 (NACHT, LRR and PYD domains-containing protein 3), otherwise known as cryopyrin, is a member of the NLR (Nod-like-receptors) family. This is a pyrin-like protein, having N-terminal CARD or pyrin domains needed for homotypic protein protein interaction, an intermediate nucleotide binding self oligomerization NACHT domain and a C-terminal domain containing leucine rich repeats (LRRs). NALP3 is a key component of innate immunity and its expression is restricted to immune cells and chondrocytes. It interacts with the apoptosis-associated speck-like protein PYCARD/ASC, which contains a caspase recruitment domain, and is a member of the NALP3 inflammasome complex. This complex functions as an upstream activator of NF-kB signaling, and it plays an important role in the regulation of inflammation, the immune response, and apoptosis.
Molekulargewicht
120 kDa
Gen-ID
114548
UniProt
Q96P20
Pathways
Cellular Response to Molecule of Bacterial Origin , Positive Regulation of Endopeptidase Activity , Inflammasome
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