MAPKAP1 Antikörper (AA 250-522)

Produktnummer ABIN5027356

Produktdetails anti-MAPKAP1 Antikörper

Target: MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))

Bindungsspezifität: AA 250-522

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPKAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant Mip1 protein (amino acids 250-522) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1-3 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu MAPKAP1

Target: MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))

Andere Bezeichnung: SAPK interacting proten 1/Mip1 (MAPKAP1 Produkte)

Synonyme: CG10105 antikoerper, Dmel\\CG10105 antikoerper, dSin1 antikoerper, sin1 antikoerper, MAPKAP1 antikoerper, im:7143088 antikoerper, si:ch73-242f23.1 antikoerper, mip1 antikoerper, sin1b antikoerper, sin1g antikoerper, MGC53034 antikoerper, JC310 antikoerper, MIP1 antikoerper, SIN1 antikoerper, SIN1b antikoerper, SIN1g antikoerper, AI591529 antikoerper, D230039K05Rik antikoerper, Sin1 antikoerper, SAPK-interacting protein 1 antikoerper, mitogen-activated protein kinase associated protein 1 antikoerper, mitogen-activated protein kinase associated protein 1 L homeolog antikoerper, Sin1 antikoerper, MAPKAP1 antikoerper, mapkap1 antikoerper, Mapkap1 antikoerper, mapkap1.L antikoerper

Hintergrund: Stress-activated map kinase (SAPK )-interacting protein 1, also called as Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1), belongs to Stress-activated map kinase interacting protein 1 (SIN1) family. It is a subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors and also plays a critical role in AKT1 'Ser-473'phosphorylation. Except isoform 4 from its 6 isoforms , all can be incorporated into the mammalian target of rapamycin complex 2 (mTORC2) which contains MTOR, MLST8, PRR5, RICTOR, MAPKAP1 and DEPTOR. It is ubiquitously expressed in heart and skeletal muscle. Diseases associated with MAPKAP1 include bronchiolitis obliterans organizing pneumonia and nephrogenic systemic fibrosis.

Molekulargewicht: 50 kDa

Gen-ID: 79109

UniProt: Q9BPZ7

Pathways: PI3K-Akt Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events