MAFA Antikörper (AA 192-353)

Produktnummer ABIN5027344

Der Kaninchen Polyklonal anti-MAFA Antikörper wird verwendet zum Nachweis von MAFA in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für MAFA Antikörper (AA 192-353) (ABIN5027344)

Target: MAFA (Transcription Factor MafA (MAFA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAFA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MAFA Antikörper

Bindungsspezifität: AA 192-353

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant Mafa protein (amino acids 192-353) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1-2 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu MAFA

Target: MAFA (Transcription Factor MafA (MAFA))

Andere Bezeichnung: Mafa

Hintergrund: Musculoaponeurotic fibrosarcoma oncogene family A (MafA) is a pancreatic transcriptional factor that is important to pancreatic beta-cell function. It is a member of the musculo-aponeurotic fibrosarcoma oncogene family, a subgroup of the basic leucine zipper transcription factors with homology to the v-Maf oncoprotein. It acts as a transcriptional regulator that promotes the expression of genes important in glucose-induced insulin secretion, such as insulin, glucokinase and glucose transporter protein-2. Mafa is unique in being exclusively expressed at the secondary and principal phase of insulin-expressing cell production during pancreas organogenesis and is the only transcriptional activator present exclusively in islet beta-cells thus may be involved in pathogenesis of diabetes.

Molekulargewicht: 36 kDa

Gen-ID: 389692

UniProt: Q8NHW3

Pathways: Hormone Transport