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MAFA Antikörper (AA 192-353)
MAFA
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5027344
Produktdetails anti-MAFA Antikörper
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Target
Alle MAFA Antikörper anzeigen
MAFA
(Transcription Factor MafA (MAFA))
Bindungsspezifität
Alle Epitope für MAFA Antikörper
AA 192-353
Reaktivität
Alle Reaktivitäten für MAFA Antikörper
Human
Wirt
Alle Wirte für MAFA Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für MAFA Antikörper
Polyklonal
Konjugat
Alle Konjugate für MAFA Antikörper
Dieser MAFA Antikörper ist unkonjugiert
Applikation
Alle Applikationen für MAFA Antikörper
Western Blotting (WB)
Aufreinigung
Protein A Chromatography
Immunogen
A partial length recombinant Mafa protein (amino acids 192-353) was used as the immunogen for this antibody.
Isotyp
IgG
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Discover our top product MAFA Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
WB: 1-2 μg/mL
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.5 mg/mL
Buffer
PBS containing 0.05 % BSA, PH 7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Details zu MAFA
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Target
MAFA
(Transcription Factor MafA (MAFA))
Andere Bezeichnung
Mafa (MAFA Produkte )
Synonyme
RIPE3b1 antikoerper, hMafA antikoerper, RGD1562627 antikoerper, 2F1-Ag antikoerper, MAFA antikoerper, MAFA-L antikoerper, SMaf1 antikoerper, mafl antikoerper, L-MAF antikoerper, MAFL antikoerper, Maf antikoerper, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian) antikoerper, MAF bZIP transcription factor A antikoerper, killer cell lectin-like receptor subfamily G, member 1 antikoerper, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A antikoerper, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa antikoerper, monocyte to macrophage differentiation-associated antikoerper, Mafa antikoerper, MAFA antikoerper, Klrg1 antikoerper, mafa antikoerper, mafaa antikoerper, Mmd antikoerper
Hintergrund
Musculoaponeurotic fibrosarcoma oncogene family A (MafA) is a pancreatic transcriptional factor that is important to pancreatic beta-cell function. It is a member of the musculo-aponeurotic fibrosarcoma oncogene family, a subgroup of the basic leucine zipper transcription factors with homology to the v-Maf oncoprotein. It acts as a transcriptional regulator that promotes the expression of genes important in glucose-induced insulin secretion, such as insulin, glucokinase and glucose transporter protein-2. Mafa is unique in being exclusively expressed at the secondary and principal phase of insulin-expressing cell production during pancreas organogenesis and is the only transcriptional activator present exclusively in islet beta-cells thus may be involved in pathogenesis of diabetes.
Molekulargewicht
36 kDa
Gen-ID
389692
UniProt
Q8NHW3
Pathways
Hormone Transport
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