MAFA Antikörper

Produktnummer ABIN7254463

Produktdetails anti-MAFA Antikörper

Target: MAFA (Transcription Factor MafA (MAFA))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAFA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Antigen affinity purification

Immunogen: Synthetic peptide of human MAFA

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, ELISA 1:5000-1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.2 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MAFA

Target: MAFA (Transcription Factor MafA (MAFA))

Andere Bezeichnung: MAFA (MAFA Produkte)

Synonyme: RIPE3b1 antikoerper, hMafA antikoerper, RGD1562627 antikoerper, 2F1-Ag antikoerper, MAFA antikoerper, MAFA-L antikoerper, SMaf1 antikoerper, mafl antikoerper, L-MAF antikoerper, MAFL antikoerper, Maf antikoerper, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian) antikoerper, MAF bZIP transcription factor A antikoerper, killer cell lectin-like receptor subfamily G, member 1 antikoerper, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A antikoerper, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Aa antikoerper, monocyte to macrophage differentiation-associated antikoerper, Mafa antikoerper, MAFA antikoerper, Klrg1 antikoerper, mafa antikoerper, mafaa antikoerper, Mmd antikoerper

Hintergrund: Members of the Maf family of basic region/leucine zipper (bZIP) transcription factors affect transcription in either a positive or negative fashion, depending on their particular protein partner and the context of the target promoter. c-Maf (Maf-2) and the closely related family members.MAFA acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity.

Molekulargewicht:

Observed_MW: Refer to figures

Calculated_MW: 37 kDa

UniProt: Q8NHW3

Pathways: Hormone Transport