KLF4 Antikörper (AA 1-300)

Produktnummer ABIN5027332

Der Kaninchen Polyklonal Anti-KLF4-Antikörper wurde für WB validiert. Er ist geeignet, KLF4 in Proben von Human zu detektieren.

Kurzübersicht für KLF4 Antikörper (AA 1-300) (ABIN5027332)

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-KLF4 Antikörper

Bindungsspezifität: AA 1-300

Aufreinigung: Protein A Chromatography

Immunogen: A partial length recombinant KLF4 protein (amino acids 1-300) was used as the immunogen for this antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 2-4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu KLF4

Target: KLF4 (Kruppel-Like Factor 4 (Gut) (KLF4))

Andere Bezeichnung: KLF4/GKLF

Hintergrund: Kruppel like factor 4 (KLF4) which are also called as gun enriched kruppel like factors (GKLF) is a member of SP/KLF family of zinc transcription factors that are involved in numerous important cellular processes, such as, proliferation, inflammation, apoptosis and somatic cell reprogramming. The Kruppel zinc finger transcription factor was initially identified in Drosophila as a segmented gene. This protein is found to inhibit cell proliferation by functioning as a cell cycle checkpoint protein that leads to activation of transcription of the cyclin-dependent kinase inhibitor. Clinically KLF4 plays a role in the pathogenesis of esophageal cancer and malaria. It has five isoform that are produced by alternate splicing. Expression of KLF4 is highly enriched in the post replicative epithelial cells of the intestine, skin and thymus.

Molekulargewicht: 55 kDa

Gen-ID: 9314

UniProt: O43474

Pathways: Peptide Hormone Metabolism, Stem Cell Maintenance